Among the various routes of drug delivery, transmucosal drug delivery offer distinct advantages over peroral administration for systemic effect. Among various transmucosal routes, buccal mucosa is the most suited for local, as well as systemic delivery of drugs. The unique physiological features make the buccal mucosa as an ideal route for mucoadhesive drug delivery system.Buccal films are the most recently developed dosage form for buccal administration. They have gained importance as efficacious and novel drug delivery systems and are cost effective with a good patient compliance.As buccal films are implied for attachment to the buccal mucosa, they can be formulated to exhibit local as well as systemic action. Buccal film may be preferred over buccal tablet, in terms of flexibility and comfort.The film can be defined as a dosage form that employs a water dissolving polymer, which allows the dosage form to quickly hydrate, adhere and dissolve when placed on the tongue, or in the oral cavity, which results in systemic drug delivery. (RadhaMadhavi B, Varanasi SN Murthy, Prameela Rani A and Dileep Kumar Gattu,Buccal Film Drug Delivery System-An Innovative and Emerging Technology) PrimeOA Publications International through its scholarly open access initiative is committed to make genuine and reliable contributions to the scientific community. It provides the best way to publish the original research work through best open access journals allowing researchers, potential learners and the academic fellow from respective domain to access the same works for free, which also results in quick dissemination of findings and a wide impact. PrimeOA Publications International handles over 700+ peer-reviewed journals through a smooth peer-review process.These journals have over 15 million readers and over 25000 eminent personalities as editorial members to its credit to promote rapid, quality and quick review processing. Alongside PrimeOA Publications Conferences division hosts about 3000+ International Scientific Conferences with numbers steadily growing each year. PrimeOA Publications International had signed agreement with more than 1000+ Scientific associations worldwide to make health care and scientific information open access.