Dental caries is one of the most common preventable childhood disease; people are liable to this ailment throughout the lifetime. Data from the National Health and Nutrition Examination Survey (NHANES) conducted between 1999 and 2004 revealed that 28 percent of children ranging from 2 to 5 years of age had one or more primary tooth affected by dental caries and 51% of children had one or more primary tooth affected by age 6 to 11. Review articles are the summary of current state of understanding on a particular research topic.