A network of fibers extending through out the cytoplasm providing structural support to cell functioning in motility, interaction with motor proteins.The major components of cytoskeleton are microtibules,microfilaments and intermediate filaments Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results. Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature.