Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) characterized by inflammation, demyelination, and axonal degeneration.1-5 Although descriptions date back as far as the Middle Ages, MS was first recognized as a distinct disease in 1868 when Jean-Martin Charcot, professor of Neurology at the University of Paris, referred to the condition as sclérose en plaques.6-8 MS affects roughly 400,000 people in the United States and 2.5 million people worldwide.2,4 MS is associated with a heterogeneous array of signs and symptoms because of involvement of the motor, sensory, visual, and autonomic systems.