Computational chemistry describes the utilization of computer modelling and simulation – including initially approaches supported quantum chemistry, and empirical approaches to review the structures and properties of molecules and materials. Computational chemistry is also used to describe the computational techniques aimed at understanding the structure and properties of molecules and materials. Computational chemists may use simulations to spot sites on protein molecules that are presumably to bind a replacement drug molecule or create models of synthesis reactions to demonstrate the effects of kinetics and thermodynamics on the amount and kinds of products. They can also explore the basic physical processes underlying phenomena such as superconductivity, energy storage, corrosion, or phase changes. The pharmaceutical industry, a serious employer of computational chemists, has historically focused on the invention and style of latest small-molecular therapeutics. Recently, however, there's a trend to use computational chemistry and cheminformatics (a field that mixes laboratory data, chemical modeling, and knowledge science methods) to process development, analytical chemistry, and biologics (medicinal products manufactured using or extracted from biological sources).