Clinical pharmacology is the science of drugs in humans and their optimal clinical use in patients. It is underpinned by the basic science of pharmacology, with an added focus on the application of pharmacological principles and quantitative methods in the real human patient's population. It has a broad scope, from the discovery of new target molecules to the effects of drug usage in whole populations. Clinical pharmacologists usually have a rigorous medical and scientific training that enables them to evaluate evidence and produce new data through well-designed studies. Clinical pharmacologists must have access to enough outpatients for clinical care, teaching and education, and research as well as be supervised by medical specialists. Their responsibilities to patients include, but are not limited to, analyzing adverse drug effects, therapeutics, and toxicology including reproductive toxicology, cardiovascular risks, preoperative drug management and psychopharmacology. Clinical pharmacology also connects the gap between medical practice and laboratory science. The main objective is to promote the safety of prescription, maximize the drug effects and minimize the side effects. In this aspect, there can be an association with pharmacists skilled in areas of drug information, medication safety and other aspects of pharmacy practice related to clinical pharmacology. In fact, in countries such as USA, Netherlands, and France, pharmacists can be trained to become clinical pharmacists, to improve optimal drug therapy with clinical pharmacology related knowledge.
In addition, the application of genetic, biochemical, or virotherapeutic techniques has led to a clear appreciation of the mechanisms involved in drug action.
A bachelor's degree, in a clinical, health science or bioscience related field is typically required for enrollment on a master's degree level course in pharmacology. Institutions may also hold specific coursework and credit requirements for enrollment on advanced degrees in pharmacology.