Clinical pharmacology is the division of pharmacology with an added focus on the applications of pharmacological principles in the medical prescription and towards the patient care and an expected beneficial outcome. It is basically the science of drugs and their clinical and medical use. It encompasses a broad scope in terms from the discovery of new target molecules to the effects of drug usage in whole populations. Clinical pharmacology connects the gap between medical practice and laboratory science. It covers the aspects of rational prescribing of drugs, drug effects, drug interactions and drug development. Rational prescribing of drugs includes using the right medication with right route, at the right dosage and frequency of administration, and finally stopping the drug appropriately. The drug development usually culminates some form of clinical trials involving drug interactions and toxicological studies. The main objective of clinical pharmacology is to promote the safety of prescribed drugs, maximize the drug effects and minimize its side effects. Clinical pharmacology studies the following aspects of a drug, such as: pharmacodynamics, pharmacokinetics, rational prescribing of the drug, ADRs, toxicology, drug interactions and drug development. The open access journals are peer reviewed scholarly journals of Clinical & Experimental Pharmacology. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in SCOPUS, COPERNICUS, CAS, EBSCO and ISI.