Chemical-pharmaceutical analysis may be defined as a procedure or the sequences of progressions to identify or quantify a constituent or drug, the mechanisms of a pharmaceutical solution or fusion or the determination of the structures of chemical combinations used in the formulation of pharmaceutical product. Innovations are new idea, device or process. innovations are the application of better solutions that meet new requirements, inarticulated needs or existing market needs. The aim of this research paper is to assess how SMEs’ internal research capacities help them to exploit external scientific and technical knowledge and to use networks of innovators. Our empirical analysis draws upon case studies made of projects which were partly financed by ANVAR, a French national agency responsible for the development of innovation projects in industry. The results of this study are three-fold.