The chemical-pharmaceutical analysis may be defined as a procedure or the sequences of progressions to identify or quantify a constituent or drug, the mechanisms of a pharmaceutical solution or fusion or the determination of the structures of chemical combinations used in the formulation of pharmaceutical product. High-impact journals are those considered to be highly influential in their respective fields. the impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. it is first devised by eugene garfield, the founder of the institute for scientific information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.