Cerebral palsy is the most prevalent cause of persisting motor function impairment. In a majority of cases, the predominant motor abnormality is spasticity; other forms of cerebral palsy include dyskinetic (dystonia or choreoathetosis) and ataxic cerebral palsy. The care of individuals with cerebral palsy should include the provision of a primary care medical home for care coordination and suppor and diagnostic evaluations. Current strategies to decrease the risk of cerebral palsy include interventions to prolong pregnancy (e.g., 17α-progesterone), limiting the number of multiple gestations related to assisted reproductive technology, antenatal steroids for mothers expected to deliver prematurely, caffeine for extremely low birth weight neonates, and induced hypothermia for a subgroup of neonates diagnosed with hypoxic-ischemic encephalopathy.