The immune device mistakenly produces the antibodies towards the fitness cells of the body. those antibodies are called auto antibodies. The antibodies which can be launched in opposition to its very own organ, tissue are called auto antibodies. these reactions motive inflammation, harm and eventually result in autoimmune diseases. There are extra than 70 forms of autoimmune diseases. till now the motive of autoimmune ailment isn't well recognise. Autoimmune diseases can be categorized in to 2 kinds a) systemic autoimmune diseases b) localized autoimmune illnesses. Systemic autoimmune diseases affect more than one organs. Localized autoimmune illnesses target one organ. Systemic lupus erythematosus comes below systemic autoimmune illnesses. Researchers observed antibodies concentrated on the host DNA in Systemic lupus erythematosus where many of these antibodies are toxic and feature the potential to penetrate in to the residing cells and nuclei. The lupus antibody, known as 3E10, is not best benign however has the potential to penetrate both wholesome and malignant cells and cell nuclei, Researchers although that 3E10 can be used as a automobile for drug shipping. They similarly observed that 3E10, when used alone, should kill cancer cells with DNA restore deficiencies along with those with mutations inside the BRCA2 gene.