Cancer has become of the dreadful diseases of all times. Despite the discovery of drugs, and the invention of other alternatives to treat cancer, the mortality rate of cancer has been increasing. Innovative cancer treatment involves the treatment of cancer by innovative methods, which would decrease the side effects and also increase efficiency in curing cancer. Surgeons often use small, thin knives, called scalpels, and other sharp tools to cut your body during surgery. Surgery often requires cuts through skin, muscles, and sometimes bone. After surgery, these cuts can be painful and take some time to recover from. Some of the innovative cancer treatments are gene therapy, immunotherapy, hormone replacement therapy, targeted drug delivery systems; Cancer vaccines are one of the innovative cancer therapies which would treat cancer in an effective way. The open-access journals are peer-reviewed scholarly journals of Biochemical engineering. The top open access Biochemical engineering journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles.