Biosafety is the prevention of large-scale loss of biological integrity, focusing both on ecology and human health. These prevention mechanisms include conduction of regular reviews of the biosafety in laboratory settings, as well as strict guidelines to follow. Biosafety is used to protect from harmful incidents .Biosafety: The application of knowledge, techniques and equipment to prevent personal, laboratory and environmental exposure to potentially infectious agents or biohazards. Biosafety defines the containment conditions under which infectious agents can be safely manipulated. The objective of containment is to confine biohazards and to reduce the potential exposure of the laboratory worker, persons outside of the laboratory, and the environment to potentially infectious agents.Biosafety is defined as, “The discipline addressing the safe handling and containment of infectious microorganisms and hazardous biological materials” . The practice of safe handling of pathogenic micro-organisms and their toxins in the biological laboratory is accomplished through the application of containment principles and the risk assessment.