Several investigations were made in recent years related to Type 3 Secretion System (T3SS) and Type 6 Secretion System (T6SS) of Vibrio parahaemolyticus. However, numerous pathogenicity islands in genomes of V. parahaemolyticus remain unexploited. Considering the presence of other secretion systems such as T1SS, T2SS, T4SS and T5SS, which are associated with the pathogenicity in other bacteria exploring the Whole Genome Sequence (WGS) data, we identified the presence of T1SS-specific Escherichia coli HlyA, and Morganella morganii Vibrio ferrin homologs in V. parahaemolyticus. The T2SS encodes tight adherence (tad) locus for bacterial adherence and production of biofilm in Actinobacillus actinomycetemcomitans. This gene locus was identified as pilin in V. parahaemolyticus. Presence of VCA0120 and csu, the pilus encoding gene homologs in the environmental V. parahaemolyticus strains supports the view that part of T4SS may be active in this Vibrio. This information should be explored further in the diseases progress using In vitro and In vivo models.