Biotechnology of biomaterials is use of metals and chemicals as Biomaterials and bio-soft-materials (bio-nano-composites) like Hy-droxyapatite, Zirconia, Alumina used in the dental implants, in turn the production of Hydroxyapatite from garden snail shell (Helix Asper-sa) is also an amazing application of biotechnology. Preceding to this Titanium in a process, induces osteoblastic bone marrow stem cells differentiation, silicone dispersions in the manufacture of murine ventricular inflating for the langendorff heart grounding, use of Gly-cine betaine as an effective compatible solute is which maintains fluidity of membranes and protects the biological structure of the organisms under stress is another criteria of biotechnological application The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information.