Clinical practice is the medical practice of by medical practitioners that involves the diagnosis, treatment, and management of patients’ medical conditions. Clinical practice guidelines are statements that include recommendations intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options. Clinical practice guidelines offer an assessment of the quality of the applicable scientific literature, and an evaluation of the possible benefits and harms of a particular treatment. This information enables health care practitioners to select the best care for a single patient based on his or her preferences.