Bioanalysis is a sub-discipline covering analytical chemistry in quantitative measurement of xenobiotics and biotics (macromolecules, proteins, DNA, large molecule drugs, metabolites) in biological systems. Bioanalysis open access journals are free online open bioanalysis journals that are available to many publishers, including financial barriers, legal outer bioanalytical access techniques, etc. enthusiasm as possible,
Many scientific efforts rely on the exact quantification of drugs and biological samples in endogenous substances; The objective of bioenergy in the pharmaceutical industry is to provide a quantitative measure of the pharmacokinetics, toxicokinetics, bioequivalence and exposure-response of the active drug and / or its metabolites. Bioanalysis also applies to drugs used for illicit purposes, forensic investigations, anti-doping tests in sport and environmental concerns.
A bioanalytical method is a set of procedures involving the collection, processing, storage and analysis of a chemical compound for a biological matrix. The Bioanalytical Method of Validation (BMV) is a quantitative analytical method that is used to establish biochemical applications. Bioanalytical chemistry is a quantitative determination of drugs and / or metabolites in biological matrices such as blood, serum, plasma or urine, tissue and skin samples applied to two bioequivalence studies, pharmacokinetics and bioavailability in animals or humans.
Bioanalysis has traditionally been used in measuring small molecule drugs. However, the past twenty years have seen an increase in biopharmaceuticals (eg proteins and peptides), which have been developed to treat many of the same diseases as small molecules. These large biomolecules presented their own unique challenges in quantification