During the last twenty years, the issues of diseases have emerged because the major constraints in cultivation business. White spot syndrome virus (WSSV), that was 1st discovered in geographic area around 1992, is presently the foremost serious microorganism microorganism of shrimp worldwide. It causes up to 100 percent mortality inside seven to ten days in business shrimp farms, leading to giant economic losses to the shrimp farming industry. WSSV belongs to a replacement virus family, the Nebaliidae, and contains an outsized circular double stranded polymer order . Shrimp culture has been a booming business since the start of the Nineteen Nineties, and worldwide production was one million metric tons in 2002 . it's one amongst the few sources for economic development and provides well-paid employment in poor coastal areas. The augmented illness occurrences have resulted within the transfer of infective organisms among countries. because of this, the shrimp business of Bharat furthermore as different Southeast Asian countries has suffered vital economic losses. As there's no effective remedies against these microorganism diseases, immuno stimulants will become powerful tools to regulate fish and shrimp diseases.