Anti-HBc is one of the test which if show positive or reactive, it means that the person being tested have HBV infection or had it at some time in the past.
The presence of anti-HBc (total) with a negative HBsAg and a negative anti-HBs indicates one of the following four things:
The patient is in a window of acute hepatitis between the elimination of HBsAg and the appearance of anti-HBs; this scenario is not observed in patients with chronic HBV infection
The patient has cleared HBV but has lost anti-HBs over the years
The patient is one of the uncommon individuals with active HBV replication who is negative for HBsAg; this situation is diagnosed when either a positive HBeAg or a positive HBV DNA result is found. The open access journals are peer reviewed scholarly journals of Biochemical engineering. The top open access Biochemical engineering journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles.