Antianginal Drugs Angina pectoris refers to a strangling or pressure-like pain caused by cardiac ischemia. The pain is usually located substernally but is sometimes perceived in the neck, shoulder and arm, or epigastrium. Women develop angina at a later age than men and are less likely to have classic substernal pain.Antianginal Drugs are those that prevent, abort or terminate attacks of angina pectoris. Types of angina – Atherosclerotic angina Attacks are predictably provoked (stable angina) by exercise, emotion, eating or coitus and subside when the increased energy demand is withdrawn. Rest, by reducing cardiac work, usually leads to complete relief of the pain within 15 min. Atherosclerotic angina constitutes about 90% of angina cases.Antianginal Drugs Vasospastic angina (rest angina, variant angina, or Prinzmetal’s angina.It Attacks occur at rest or during sleep and are unpredictable. Vasospastic angina is responsible for less than 10% of angina cases. Coronary artery calibre changes in classical and variant angina