There are several diseases in ancient days, to which individuals got affected, suffered and died too. These ancient diseases caused by microbes are divided into sub categories depending abreast of the source through which they need affected people. Those are Food and water borne diseases, air borne diseases, vector borne diseases, etc. Although we got succeeded in curing these ancient diseases, by the grace of medicines and antibiotics, microbes are still emerging day by day by showing many mutations and have becoming an ever green challenge to the present scientific community. These ancient diseases caused by microbes are divided into sub categories depending abreast of the source through which they need affected people. Those are Food and water borne diseases, air borne diseases, vector borne diseases, etc. Diseases spread through Food and water is usually referred to as Food and water borne diseases