A serious allergy that onsets rapidly and may be even fatal is named anaphylaxis. It causes variety of symptoms, typically consisting of throat swelling, itchy rashes and low vital sign . Insect bites or stings, foods and medications are a number of the common causes. Its mechanism are often explained as a reaction occurring due to release of mediators or signals from certain white cells. this might be triggered by either an immunologic or non-immunologic mechanisms. Anaphylaxis are often diagnosed counting on the exhibited signs and symptoms. Administration of intravenous fluids, positioning of the patient flat and epinephrine injections could also be considered as primary treatment. Other measures can also be used as a complementary action. Scholarly referee is that the process of subjecting an author's scholarly work, research, or ideas to the scrutiny of others who are experts within the same field, before a paper describing this work is published during a journal.