Androgenetic alopecia (AGA) is one of the most well-known dermatologic issue with a multifactorial etiology. Incendiary activators, for example, Demodex pervasion may assume a job in the pathogenesis of certain instances of androgenetic alopecia that don't react to basic medicines, for example, minoxidil and finasteride. The objective of this investigation is to assess the connection between Demodex invasion and AGA. Materials and Methods: For this situation control study, 41 patients with AGA alluded to the Dermatology Clinic of Imam Reza Hospital and 33 sound people were assessed as control. Every one of them were somewhere in the range of 20 and 40 years of age men. So as to recognize Demodex invasion they were alluded to the Parasitology lab. Results: Demodex was distinguished in 19.5% of patients and 15.2% of controls; accordingly, there was no noteworthy connection between them measurably ( P = 0.0787). The vast majority of patients (85.4%) had oily hair. The most well-known example of hairlessness was II degree in Hamilton scale. End: There is no connection among AGA and Demodex. Androgenetic alopecia (AGA) is one of the most widely recognized dermatologic issue, which is concerned more recently.Various speculations have been advanced on the AGA causes, out of which none of them has a 100% job in it. As per our insight, the meddling components are hormones, receptors, heredity and microbial greenery. An examination on twins shows that inclination, time of beginning, example and movement pace of AGA are reflected by hereditary qualities. Treatment with antihypertensitive specialists, for example, minoxidil or modulators of androgen digestion, for example, finasteride are scarcely compelling on 30%; this suggests different pathways might be imagined. These days, aggravation has been viewed as associated with pathogenesis of this issue. In a few investigations on hair follicles taken from subjects with AGA a moderate perifollicular lymphohistiocytic irritation in 30% of AGA and 15% of control cases is watched.