Immunotherapy is a preventive treatment for allergic reactions to substances such as grass pollens, house dust mites and bee venom. Immunotherapy involves giving gradually incrementing doses of the substance, or allergen, to which the person is allergic. In desensitization immunotherapy the aim is to induce or renovate tolerance to the allergen by minimizing its proclivity to induce IgE engenderment. People are desensitized through the administration of escalating doses of allergen that gradually decreases the IgE-dominated replication. You may be able to minimize your symptoms enough utilizing over-the-counter allergy drugs. If not, your medico can prescribe medication. You can withal verbalize with an allergist about immunotherapy in the form of allergy shots or oral tablets or drops. These are what are considered disease modifying treatments. Authors may submit manuscripts and track their progress through the online tracking system. To increment the overtness and facilitate of avail of open access scientific and scholarly journals top online publishing journals are indexed in different indexing and archiving accommodations. Indexing provides facile access of the article online. The top online publishing journals publish articles which are cited as references by many authors in their work. The citations are consequential for a journal to get impact factor. To increment the overtness and facilitate of avail of open access scientific and scholarly journals top online publishing journals are indexed in different indexing and archiving accommodations. Indexing provides facile access of the article online. The top online publishing journals publish articles which are cited as references by many authors in their work. The citations are consequential for a journal to get impact factor. Impact factor is a quantification reflecting the average number of citations to recent articles published in the journal. The international journals are among the best open access journals in the world, set out to publish the most comprehensive, germane and reliable information predicated on the current research and development on a variety of subjects. To increment the overtness and facilitate of avail of open access scientific and scholarly join. The top online publishing journals publish articles. This information can be published in our peer reviewed journal with impact factors and are calculated utilizing citations not only from research articles but withal review articles, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and endeavor to increment their number expeditiously. To increment the overtness and facilitate of avail of open access. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and endeavor to increment their number expeditiously. Impact factor plays a major role for the particular journal. Allergy and therapy is peer reviewed journals works to publish most reliable and consummate source of information regarding advance revelations and development in the path allergy and therapy.