Aldosterone is produced by the adrenal cortex. It helps in the regulation of blood pressure by acting on the distal tubules and collecting ducts of the nephrons which increases the re-absorption of ions and water in the kidneys. This leads to the secretion of potassium, conservation of sodium, increased blood pressure and retention of water. Aldosterone can be pathogenic if not regulated properly. It may also contribute to the development and progression of renal and cardiovascular diseases. The top open access journals are peer reviewed scholarly journals of Journal of Allergy and Therapy. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in MEDLINE, PUBMED, SCOPUS, COPERNICUS, CAS, EBSCO and ISI.