Announcing antagonistic medication responses (ADR) precipitously is considered as a foundation of Pharmacovigilance. The achievement of ADR announcing relies upon co-activity and inspiration and it is duty of the social insurance experts to identify, explore, oversee and report unfriendly medication responses. Wubshet Hailu, Knowledge, mentality and practices of Ethiopian wellbeing proficient towards unfavorable medication response reporting.Adverse tranquilize responses (ADRs) are worldwide general medical issues. In its extreme structure it might cause medical clinic confirmation, dreariness and mortality. Early announcing of suspected ADRs to administrative specialists is known to be fitting measure toinsure wellbeing and security of open structure such unfavorable medication response of medications. In Addis Ababa, there is constrained data on ADR announcing rehearses among clinical specialists. Henceforth, this examination expected to evaluate ADR detailing rehearses and related elements among specialists in government clinics in Addis Ababa.Adverse medicate response revealing practice among specialists wasfound to be low. Sex, level of training, work understanding, presence of detailing structure and answering to promoting approval holderswere essentially connected with ADR revealing practice. Moreover, there are holes in availabilities of rules, detailing frameworks and structure, pre-administration and in-administration preparing, and familiarity with specialists on effect of announcing. Henceforth, improving access to ADR announcing structure, decentralize security checking framework, and leading mindfulness preparing on ADR revealing are basic to improve the ADR detailing practice.