Declaring adversarial drug reactions (ADR) abruptly is considered as an establishment of Pharmacovigilance. The accomplishment of ADR declaring depends upon co-movement and motivation and it is obligation of the social protection specialists to recognize, investigate, manage and report disagreeable prescription reactions. Wubshet Hailu, Knowledge, attitude and practices of Ethiopian prosperity capable towards ominous prescription reaction reporting.Adverse sedate reactions (ADRs) are overall general clinical issues. In its extraordinary structure it may cause clinical facility affirmation, inauspiciousness and mortality. Early reporting of suspected ADRs to managerial experts is known to be fitting measure toinsure prosperity and security of open structure such troublesome prescription reaction of drugs. In Addis Ababa, there is obliged information on ADR declaring practices among clinical pros. Hereafter, this assessment expected to assess ADR enumerating practices and related components among pros in government facilities in Addis Ababa.Adverse sedate reaction uncovering practice among authorities wasfound to be low. Sex, level of preparing, work understanding, nearness of enumerating structure and offering an explanation to advancing endorsement holderswere basically associated with ADR uncovering practice. Also, there are openings in availabilities of rules, enumerating systems and structure, pre-organization and in-organization getting ready, and nature with masters on impact of declaring. From now on, improving access to ADR declaring structure, decentralize security checking system, and driving care getting ready on ADR uncovering are essential to improve the ADR enumerating practice.