Acrokeratosis verruciformis is an uncommon genodermatosis with an autosomal predominant method of legacy. Acrokeratosis verruciformis is a turmoil of keratinization portrayed by different level beat, skin-shaded keratotic sores looking like plane moles regularly saw on the dorsum of the hands and feet. Hopf first recommended the name acrokeratosis verruciformis in 1931.In 1947, Niedleman first distributed the biggest arrangement portraying an Italian American family in which acrokeratosis verruciformis of Hopf happened in 14 individuals. In the subsequent investigation in 1962, Niedleman and McKusick further depicted 24 cases in 4 ages of a similar family.The number and circulation of cases in the last report proposed an autosomal prevailing method of transmission. Injuries indistinguishable from those of acrokeratosis verruciformis are additionally seen in numerous patients with acral Darier infection (likewise named keratosis follicularis) or even in family members of people with Darier ailment.Significant contention encompasses the nature and relationship of acrokeratosis and Darier malady and whether they are appearances of one hereditary variation from the norm