Drug delivery is a means in which magnetic particles such as iron oxide nanoparticles are a component of a delivery vehicle for magnetic drug delivery, due to their easiness and simplicity with magnet-guidance.Magnetic nanoparticles can impart imaging and controlled release capabilities to drug delivery materials such as micelles liposomes, and polymers.Molecular magnets (single-molecule magnets) are a platform that incorporates insoluble (toxic) drugs into biocompatible carrier materials, without adding magnetic iron oxide nanoparticles, in which adversely affecting potential side effects attributed to iron overdose as well as low drug loading efficiency. The drawbacks in conventional magnetic drug delivery methods can be overcame by switching from typical iron oxide nanoparticles to ones based on molecular magnet, such as Fe(salen)-based "anticancer nanomagnet with proven cancer-fighting ability. However, insoluble drugs including Fe(salen) also have some inherent drawbacks, such as poor water solubility, loss of magnetic activity in solvents, and potential cytotoxicity when accumulated in tissues and organs