A bone marrow transplant is a procedure used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Bone marrow is the soft, fatty tissue inside your bones which produces blood cells. Stem cells are immature cells in the bone marrow that give rise to different blood cells. Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. A bone marrow transplant, also called a stem cell transplant, is a treatment for some types of cancer. For example, you might have one if you have leukemia, multiple myeloma, or some types of lymphoma. Doctors also treat some blood diseases with stem cell transplants. In the past, a stem cell transplant was more commonly called a bone marrow transplant because the stem cells were collected from the bone marrow. Today, stem cells are usually collected from the blood, instead of the bone marrow. For this reason, they are now often called stem cell transplants.
Before transplant, patient will get chemotherapy (chemo) with or without radiation to destroy the diseased blood-forming cells and marrow. Then, healthy cells are given to you (it’s not surgery). The new cells go into your bloodstream through an intravenous (IV) line, or tube. It’s just like getting blood or medicine through an IV. The cells find their way into your marrow, where they grow and start to make healthy red blood cells, white blood cells and platelets. Bone marrow transplants can treat diseases such as: leukemia or lymphoma, aplastic anemia, Other immune system or genetic diseases like sickle cell disease etc.
List of Academic Journals In Bone Marrow Transplantation:
Advances in Hematology. American Journal of Hematology. American Journal of Stem Cell Research. Annals of Hematology. Biology of Blood and Marrow Transplantation. Blood. Blood Cells, Molecules, and Diseases. Blood Reviews.