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Experts in Immunology
Priti Bajpai M.J.M. (MARC) BONTEN Rolee Sharma Douglas Darling Donald Demuth Alba Ruiz de Andrés Javier MartÃnez-Picado Prof. Sarat Kumar Dalai Prof. Sarat Kumar Dalai Julià Blanco Cezmi A. Akdis Dr Joanna Kirman Arianna Calcinotto Dennis W. McGee Liz Hedstrom Daniela Brina Joan Press Neil E. Simister Mausumi Sikdar (Nee Bhakta ) Asmita Das View MoreXiuli An
Head
Complement Biology
Complement Biology, New York Blood Center
United States of America
Dr. An’s research is focused on developing a detailed molecular understanding of regulation of erythropoiesis. Her lab has developed methods to purify both human and mouse erythroid cells at distinct developmental stages and methods to quantify the progress of erythroid differentiation in vivo. Through RNA-seq analysis, her lab constructed global transcriptomesof human and murine erythroid cells. Based on the development of these novel methodology and database, Dr. An’s lab is currently working on three areas: 1) studying regulation of erythropoiesis by epigenetic modifiers such as methylcytosine dioxygenase TET2 and TET3; 2) Identifying the contribution of commonly mutated epigenetic modifiers to the dyserythropoiesis of myelodysplastic syndromes patients; 3) Improving red cell production ex vivo from stem cells.
Biochemistry