Vassilis Aidinis

Head
Division of Immunology
Biomedical Sciences Research Center Alexander Fleming
Greece

Biography

 Dr. Aidinis received his B.Sc. in Biology from the University of Patras and his Ph.D in Molecular Biology from the University of Athens. He received his Ph.D training at the National Hellenic Research Foundation, where his work focused on the isolation and characterization of a novel heterogeneous nuclear RNP. At the same time and in collaboration with the Medical School of the University of Athens, he investigated various aspects of the involvement of snRNPs in autoimmunity. During his post-doctoral appointment at the D.H.R. Cancer Center of Mount Sinai’s School of Medicine, Howard Hughes Medical Institute, New York, his work focused on the biochemistry of V(D)J recombination and the involvement of chromatin architectural factors at the initial stages of the reaction. During his second postdoctoral appointment at the Molecular Genetics Laboratory of Hellenic Pasteur Institute, he explored the role of the synovial fibroblast in the pathogenesis of Rheumatoid Arthritis where, among others, he introduced the study of differential gene expression analysis. In 2001 he was appointed as a researcher C’ (eq. assistant professor, tenure track) at the Institute of Immunology, BSRC Fleming, where he committed his research efforts in deciphering the pathogenetic mechanisms governing chronic inflammation disorders (such as rheumatoid arthritis and idiopathic pulmonary fibrosis), as well as in establishing and developing the technology of DNA microarrays and related computational tools. In 2006 he was appointed as a researcher B’ and in 2012 as a Researcher A’ (eq. professor, tenure) at the Division of Immunology, BSRC Fleming, where he continues his research endeavors, currently focusing on two pillars: 1) the molecular and genetic dissection of pathogenetic mechanisms in the development of pulmonary inflammation, fibrosis and cancer, 2) the investigation of the role of autotaxin and phospholipid signalling in chronic inflammation and cancer.    

Research Intrest

 Pathogenetic mechanisms,  computational tools and cancer