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Thomas R. O Brien

Senior Investigator
Division of Cancer Epidemiology, Infections and Immunoepidem
National Cancer Institute
United States of America

Scientist Medical Sciences
Biography

Dr. O'Brien received undergraduate and medical degrees from the University of Michigan, and an M.P.H. from the Harvard School of Public Health. He was an Epidemic Intelligence Service Officer and Medical Epidemiologist with the Centers for Disease Control and Prevention before joining the NIH Intramural Research Program in 1992. His primary research interests have involved studies on the transmission and natural history of oncogenic viruses, including human immunodeficiency virus type 1, hepatitis B virus and hepatitis C virus (HCV).

Research Intrest

chronic hepatitis; human genetics

List of Publications
O Brien TR. Interferon-alfa, interferon-λ and hepatitis C. Nature genetics. 2009 Oct 1;41(10):1048-50.
O brien TR, Feld JJ, Kottilil S, Pfeiffer RM. No scientific basis to restrict 8 weeks of treatment with ledipasvir/sofosbuvir to patients with hepatitis C virus RNA< 6,000,000 IU/mL. Hepatology. 2016 Jan 1;63(1):28-30.
O brien TR, Lang Kuhs KA, Pfeiffer RM. Subgroup differences in response to 8 weeks of ledipasvir/sofosbuvir for chronic hepatitis C. InOpen forum infectious diseases 2014 Dec 1 (Vol. 1, No. 3). Oxford University Press.

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