Sheldon S Miller

Senior Investigator
Section on Epithelial and Retinal Physiology and Disease
National Eye Institute
United States of America

Scientist Ophthalmology
Biography

Dr. Miller received his B.S. in physics from Case Institute of Technology, his M.S. in elementary particle physics from Ohio State University, and Ph.D. in biophysics from the University of Michigan. His post- doctoral work was at the University of California, San Francisco, in the Department of Ophthalmology where he carried out with Roy Steinberg the first studies on retinal pigment epithelial transport. Dr. Miller was appointed as an assistant professor in the Vision Science Program and The School of Optometry at UC Berkeley, and full professor in 1984. In 1988, he was appointed professor in the Department of Molecular and Cell Biology at UC Berkeley. His honors include a NIH - Research Career Development Award and a NIH - MERIT Award. In 2002, he was recruited as Director of Intramural Research in the National Eye Institute. Dr. Miller’s research interests have focused on understanding the function and regulation of epithelia from breast, lung, and eye with particular interest in the pathophysiology associated with disease processes such as breast cystic disease, cystic fibrosis, and retinal degenerative diseases leading to abnormal fluid accumulation in retina and subretinal space.

Research Intrest

Ophthalmology

List of Publications
Strunnikova NV, Maminishkis A, Barb JJ, Wang F, Zhi C, Sergeev Y, Chen W, Edwards AO, Stambolian D, Abecasis G, Swaroop A. Transcriptome analysis and molecular signature of human retinal pigment epithelium. Human molecular genetics. 2010 Apr 1;19(12):2468-86.
Bharti K, Miller SS, Arnheiter H. The new paradigm: retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells. Pigment cell & melanoma research. 2011 Feb 1;24(1):21-34.
Li R, Wen R, Banzon T, Maminishkis A, Miller SS. CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium. PloS one. 2011 Sep 2;6(9):e23148.