Head
Complement Biology
Complement Biology, New York Blood Center
United States of America
The focus of our lab’s research is to find novel means to support the prevention ofonchocerciasis, also known as river blindness, and lymphatic filariasis, also known as elephantiasis. To achieve this we have been studying the biology of Onchocerca volvulusand Brugia malayi, the causative agents of these diseases, respectively. Information gained by studying the basic biology and host-parasite interactions has allowed the identification of key pathways and molecules that are essential for parasite development, propagation and /or survival. While many aspects of our research are basic, our ultimate goal is to identify new strategies by which humans can be protected from these parasitic infections by either chemotherapeutic (drugs) or immunological (vaccines) means.
Molecular Parasitology