Sara Lustigman

Head
Complement Biology
Complement Biology, New York Blood Center
United States of America

Scientist Immunology
Biography

The focus of our lab’s research is to find novel means to support the prevention ofonchocerciasis, also known as river blindness, and lymphatic filariasis, also known as elephantiasis. To achieve this we have been studying the biology of Onchocerca volvulusand Brugia malayi, the causative agents of these diseases, respectively. Information gained by studying the basic biology and host-parasite interactions has allowed the identification of key pathways and molecules that are essential for parasite development, propagation and /or survival. While many aspects of our research are basic, our ultimate goal is to identify new strategies by which humans can be protected from these parasitic infections by either chemotherapeutic (drugs) or immunological (vaccines) means.

Research Intrest

Molecular Parasitology

List of Publications
O Connell EM, Kamenyeva O, Lustigman S, Bell A, Nutman TB (2017) Defining the target and the effect of imatinib on the filarial c-Abl homologue. PLoS Negl Trop Dis 11: e0005690.
Bottomley C, Isham V, Vivas-Martínez S, Kuesel AC, Attah SK, et al. (2017) Response to the Letter to the Editor by Eberhard et al. Parasit Vectors 10: 240.