Roman Tremmel

Scientist
Department of Clinical Pharmacology
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology
Germany

Biography

He is currently scientist at the Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart and University of Tübingen. Done PhD thesis (Prof. Dr. U.M. Zanger) “Preliminary: Bioinformatic analysis and characterization of genomic structural variants in ADME genes in human liver” and scientist (Prof. Dr. M. Schwab) at the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology.

Research Intrest

Pharmacogenetics and genomics

List of Publications
Tamm R, Magi R, Tremmel R, Winter S, Mihailov E, Smid A, Moricke A, Klein K, Schrappe M, Stanulla M, Houlston R, Weinshilboum R, Mlinaric Rascan I, Metspalu A, Milani L, Schwab M, Schaeffeler E (2016) Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: a meta-analysis of three genome-wide association studies. Clin Pharmacol Ther.10.1002/cpt.540
Zanger, U.M., Klein, K., Thomas, M., Rieger, J.K., Tremmel, R., Kandel, B.A., Klein, M., and Magdy, T. (2014). Genetics, epigenetics, and regulation of drug-metabolizing cytochrome p450 enzymes. Clin. Pharmacol. Ther. 95, 258–261.
Tremmel R, Klein K, Winter S, Schaeffeler E, Zanger UM (2016) Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1. Pharmacogenomics J 16(6):551–558

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