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Experts in Genetics
Sanjay Gupta Aimée M. Dudley David Buchanan Drena Dobbs Karin S Dorman Dr. Xun Gu Thomas Peterson IRFAN AHMAD ANSARI John Golin Jannice Friedman Vimla Aggarwal Andrea Rinaldi Carmen Argmann Eleanor Maine Albertini Alessandra Judith Greenberg Mark Clark John F. Hayes Ashok Kumar Roger I. Cue View MoreMy research focuses on investigating the structure and function of RNA polymerases (RNAPs). These enzymes play a key role in the regulation of gene expression programs under normal and pathological conditions. During the last decade we have developed numerous unique methodologies. These currently include the in vitro assembly of functional RNAPs from recombinant subunits, high-throughput (robot-assisted) mutagenesis profiling fo protein domains and sophisticated molecular dynamics analyses.
My research focuses on investigating the structure and function of RNA polymerases (RNAPs). These enzymes play a key role in the regulation of gene expression programs under normal and pathological conditions. During the last decade we have developed numerous unique methodologies. These currently include the in vitro assembly of functional RNAPs from recombinant subunits, high-throughput (robot-assisted) mutagenesis profiling fo protein domains and sophisticated molecular dynamics analyses.