MD degree, University of Catania, School of Medicine, 1980. Specialist Endocrinologist University of Catania, School of Medicine, 1983. Visiting Fellow, Weizmann Inst Science, Rehovot, IL, (1983-1984). Post-doctoral Fogarty Fellow, NIH, Bethesda USA, 1985-1989 Proinflammatory cytokines and the neuroendocrine system). Assistant Professor of Catania Sch Med (1989-1991). Associate Prof of Pharmacology, University of Catania Sch Med (1992-2001). Lecturer in Neuropsychopharmacology, University of Pisa School of Sciences, 1998-2000. Full Prof of Pharmacology, Univ Catania Sch Med (2001-present). Chairman, PhD program in Preclinical and Clinical Pharmacology, University of Catania School of Medicine, 1998-present. Visiting Professor, Hebrew University, Jerusalem 2001-2002. Chairman, School of Specialization in Medical Toxicology, Univ Catania Sch Med (2000-2006). Recipient of research grants from: University of Catania, MIUR, CNR, European Union, Regione Siciliana, AIRC, other private research Institutions.

Cellular and Molecular Pharmacology: Role of cytokines in models of pathophysiology of neurodegenerative disorders and related pharmacological strategies; Control of tumor angiogenesis and cell proliferation and related pharmacotherapeutic strategies. Clinical Pharmacology and post-marketing surveillance; Clinical toxicology and pharmacogenetics