Biography

Dr. Aplan received a B.S. in biophysics (1979) and an M.D. (1983) from Pennsylvania State University in 1983. From 1983 to 1987, he trained in pediatrics and was chief resident at the Children's Hospital of Buffalo. He received fellowship training in pediatric hematology/oncology at the NCI from 1987 to 1992 and served as assistant, then associate, professor of pediatrics and microbiology and immunology at Roswell Park Cancer Institute from 1992 to 1999. He moved to the NCI in 1999 where he is an investigator in the Genetics Branch. 

Research Intrest

Cancer Biology, Chromosome Biology, Developmental Biology, Genetics and Genomics, Stem Cell Biology 

List of Publications
Onozawa M, Zhang Z, Kim YJ, Goldberg L, Aplan PD (2014) Repair of DNA double-strand breaks by templated nucleotide sequence insertions derived from distant regions of the genome. Proc. Natl. Acad. Sci. U.S.A. 111: 7729-7734.
Gough SM, Slape CI, Aplan PD (2011) NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights. Blood. 118: 6247-6257.
Chung YJ, Choi CW, Slape C, Fry T, Aplan PD (2008) Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell. Proc. Natl. Acad. Sci. U.S.A. 105: 14088-14093