Lance M Optican

Senior Investigator
Neural Modeling Section
National Eye Institute
United States of America

Scientist Ophthalmology
Biography

Dr. Optican received a B.Sc. degree from the California Institute of Technology in 1972, and a Ph.D. degree in Biomedical Engineering from the Johns Hopkins School of Medicine in 1978. His thesis work with Professor David A. Robinson was on the adaptive control of saccadic eye movements by the cerebellum. He then did a post-doctoral fellowship at NIMH with Dr. F. A. Miles, during which he studied visual influences on adaptive control of saccades. In 1979 Dr. Optican joined the NEI, and in 1985 he became chief of the Section on Neural Modeling in the Laboratory of Sensorimotor Research. His laboratory focuses on experimental and theoretical studies of sensory and motor aspects of normal, adaptive and impaired rapid eye and head movements.

Research Intrest

Ophthalmology, Neural control of eye movements, Neuroscience and Biomedical Engineering

List of Publications
Ramat S, Leigh RJ, Zee DS, Optican LM. What clinical disorders tell us about the neural control of saccadic eye movements. Brain. 2006 Nov 21;130(1):10-35.
Daye PM, Optican LM, Blohm G, Lefevre P. Hierarchical control of two-dimensional gaze saccades. Journal of computational neuroscience. 2014 Jun 1;36(3):355-82.
Pretegiani E, Rosini F, Rocchi R, Ginanneschi F, Vinciguerra C, Optican LM, Rufa A. GABAAergic dysfunction in the olivary-cerebellar-brainstem network may cause eye oscillations and body tremor. Clinical Neurophysiology. 2017 Mar 1;128(3):408-10.