Lai Liangxue

Principal Investigator
Stem Cell Biology and Regenerative Medicine.
GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH
China

Scientist Medicine
Biography

Lai Liangxue had completed his Ph.D from Northeast Agricultural University in China.He is a Postdoctoral Fellow in Molecular Biology Laboratory from Changchun University of Agriculture and Animal Sciences. Research Assistant Professor in Animal Science Research Center in the University of Missouri-Columbia, Research Assistant Professorin National Swine Resource and Research Centerin the University of Missouri-Columbia.

Research Intrest

Dr. Lai’s lab is focusing on transgenic animals, animal cloning human and animal stem cells,. In 2002, Dr. Lai and his team made the first knock-out pigs in the world by using nuclear transfer approach, in which α -1,3-Galactosyltransferase gene was deleted ,and considered as a major breakthrough in the organ transplantation from pigs to human. As of now, his team has produced more than 20 kind of transgenic pigs with important applications in biomedicine and agriculture. He has published more than 70 peer review papers in the international journals including “Science”, “PNAS”, “Nature Biotechnology” and “Human Molecular Genetics”. In addition, as principal investigator, he has been undertaking many national major scientific research programs, such as 973 program (National Program on Key Basic Research Projects), 863 Program (National High-tech R&D Program of China), National Nature Science Foundation of China, etc.

List of Publications
Esteban MA, Xu J, Yang J, Peng M, Qin D, et al.(2009) Generation of induced pluripotent stem cell lines from Tibetan miniature pig. Biol Chem 284: 17634-17640.
Chen J, Liu J, Han Q, Qin D, Xu J, et al. (2010) Towards an optimized culture medium for the generation of mouse induced pluripotent stem cells. J Biol Chem 285: 31066-31072.
Li L, Pang D, Wang T, Li Z, Chen L, et al. (2009) Production of a reporter transgenic pig for monitoring Cre recombinase activity. Biochem Biophys Res Commun 382: 232-235.