Joost J. Oppenheim

Cancer and Inflammation Program
The Center for Cancer Research
United States of America

Scientist Immunology

Biography

Dr. Oppenheim obtained his M.D. degree from the Columbia College of Physicians and Surgeons, New York, trained as a clinical associate at the National Cancer Institute (NCI), Bethesda, Maryland, and was a postdoctoral fellow at the University of Birmingham, England, in immunology. He returned to the National Institute of Dental Research and subsequently headed the Section of Cellular Immunology there and, since 1983, has been head of the Laboratory of Molecular Immunoregulation, NCI-Frederick.

Research Intrest

Cancer Biology, Immunology, Molecular Biology and Biochemistry

List of Publications

Tewary P, de la Rosa G, Sharma N, Rodriguez LG, Tarasov SG, et al. (2013) Î²-Defensin 2 and 3 promote the uptake of self or CpG DNA, enhance IFN-Î± production by human plasmacytoid dendritic cells, and promote inflammation. J. Immunol. 191: 865-874.

Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, et al. (2014) Effective chemoimmunotherapy with anti-TGFÃŸ antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE. 9: e85398.

Jelacic TM, Chabot DJ, Bozue JA, Tobery SA, West MW, et al. (2014) Exposure to Bacillus anthracis capsule results in suppression of human monocyte-derived dendritic cells. Infect Immun. 82: 3405-16.

Wei F, Yang D, Tewary P, Li Y, Li S, et al. (2014) The Alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant. Cancer Res. 74: 5989-5998.

Chen X, Willette-Brown J, Wu X, Hu Y, Howard OM, et al. (2015) IKKÎ± is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells. FASEB J. 29: 443-454.

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Experts in Immunology

Joost J. Oppenheim

Tewary P, de la Rosa G, Sharma N, Rodriguez LG, Tarasov SG, et al. (2013) Î²-Defensin 2 and 3 promote the uptake of self or CpG DNA, enhance IFN-Î± production by human plasmacytoid dendritic cells, and promote inflammation. J. Immunol. 191: 865-874.

Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, et al. (2014) Effective chemoimmunotherapy with anti-TGFÃŸ antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE. 9: e85398.

Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, et al. (2014) Effective chemoimmunotherapy with anti-TGFÃŸ antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE. 9: e85398.

Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, et al. (2014) Effective chemoimmunotherapy with anti-TGFÃŸ antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE. 9: e85398.

Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, et al. (2014) Effective chemoimmunotherapy with anti-TGFÃŸ antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE. 9: e85398.

Chen X, Yang Y, Zhou Q, Weiss JM, Howard OZ, et al. (2014) Effective chemoimmunotherapy with anti-TGFÃŸ antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE. 9: e85398.

Jelacic TM, Chabot DJ, Bozue JA, Tobery SA, West MW, et al. (2014) Exposure to Bacillus anthracis capsule results in suppression of human monocyte-derived dendritic cells. Infect Immun. 82: 3405-16.

Wei F, Yang D, Tewary P, Li Y, Li S, et al. (2014) The Alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant. Cancer Res. 74: 5989-5998.

Chen X, Willette-Brown J, Wu X, Hu Y, Howard OM, et al. (2015) IKKÎ± is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells. FASEB J. 29: 443-454.

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