Dr. Hofmann received his Ph.D. in epidemiology from the University of Washington, where he conducted a longitudinal molecular epidemiologic study of organophosphate-exposed agricultural pesticide handlers for his dissertation research. After completing his doctoral degree in 2008, Dr. Hofmann joined the Occupational and Environmental Epidemiology Branch (OEEB) as a postdoctoral fellow. He became a research fellow in 2011 and was appointed to the position of tenure-track investigator in 2015. He has received several awards recognizing his research, including the NCI Director’s Intramural Innovation Award, the AACR Scholar-in-Training Award, and Fellows Awards for Research Excellence from both the National Institutes of Health and the Division of Cancer Epidemiology and Genetics.

Dr. Hofmann's research is focused on evaluating the role of agricultural exposures in the etiology of multiple myeloma and other cancers, and on understanding the biological mechanisms that influence the development and progression of multiple myeloma. He is also investigating the etiology of renal cell carcinoma using both classical and molecular epidemiologic approaches