Howard A. Young

Head, Cellular and Molecular Immunology Section
The Center for Cancer Research
United States of America

Scientist Immunology
Biography

Dr. Howard Young obtained his Ph.D. in microbiology at the University of Washington and carried out postdoctoral research at the NCI under Drs. Edward Scolnick and Wade Parks. He was a member of the Laboratory of Molecular Immunoregulation at NCI from 1983 to 1989 prior to joining the Laboratory of Experimental Immunology in 1989. He was President of the International Society for Interferon and Cytokine Research (2004-2005) and served as Chair of the Immunology Division of the American Society for Microbiology. He has also served as Chair of the NIH Cytokine Interest Group and Co-Chair of the NIH Immunology Interest Group. He is a two-time recipient of the NIH Director's Award for Mentoring (2000, 2006) and in 2006 he received the National Public Service Award. In 2007 he was named Deputy Chief of the Laboratory of Experimental Immunology. 

Research Intrest

Cancer Biology, Cell Biology, Immunology, Molecular Biology and Biochemistry 

List of Publications
Savan R, McFarland AP, Reynolds DA, Feigenbaum L, Ramakrishnan K, et al. (2011) A novel role for IL-22R1 as a driver of inflammation. Blood. 117: 575-84.
McLean MH, Dieguez D Jr, Miller LM, Young HA (2015) Does the microbiota play a role in the pathogenesis of autoimmune diseases?. Gut. 64: 332-341.
McFarland AP, Savan R, Wagage S, Addison A, Ramakrishnan K, et al. (2011) Localized delivery of interferon-beta by Lactobacillus exacerbates experimental colitis. PLoS ONE. 6: e16967.
Hodge DL, Berthet C, Coppola V, Kastenmüller W, Buschman MD, et al. (2014) IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice. J. Autoimmunity. 53: 33-45.
Lin FC, Karwan M, Saleh B, Hodge DL, Chan T, et al. (2014) IFN-γ causes aplastic anemia by altering hematopoiesis stem/progenitor cell composition and disrupting lineage differentiation. Blood. 53: 33-45.