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Grocholski Thadee

Senior Research Scientist
Biochemistry
University of Turku
Finland

Scientist Biochemistry
Biography

Dr.Grocholski Thadee is currently working as a Senior Research Scientist for the Project 'Antibiotic Biosynthetic Enzymes (ABE)' in the Department of Biochemistry,University of Turku.Dr.Grocholski's research interests includes enzymology of Type II aromatic polyketide biosynthesis in Streptomyces bacteria.

Research Intrest

Enzymology of Type II aromatic polyketide biosynthesis in Streptomyces bacteria

List of Publications
Koskiniemi H, Grocholski T, Schneider G, Niemi J. Expression, purification and crystallization of the cofactor-independent monooxygenase SnoaB from the nogalamycin biosynthetic pathway. Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2009 Mar 1;65(3):256-9.
Grocholski T, Koskiniemi H, Lindqvist Y, Mäntsälä P, Niemi J, Schneider G. Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: implications for the reaction mechanism. Biochemistry. 2010 Jan 12;49(5):934-44.
Grocholski T, Oja T, Humphrey L, Mäntsälä P, Niemi J, Metsä-Ketelä M. Characterization of the two-component monooxygenase system AlnT/AlnH reveals early timing of quinone formation in alnumycin biosynthesis. Journal of bacteriology. 2012 Jun 1;194(11):2829-36.

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