Giuseppina Carbone

Managing Director
Prostate Cancer Biology
Oncology Institute of Southern Switzerland
Switzerland

Scientist Oncology

Biography

Giuseppina Carbone obtained her MD degree in 1983 and completed her clinical residency in 1987 at the University of Naples Medical School, Naples, Italy. In 1988 she moved to the USA and trained in basic research at Wake Forest University Medical Center (Winston-Salem, NC) in the Department of Physiology Pharmacology. From 1994 she was senior fellow at the Hollings Cancer Center in the Department of Experimental Oncology of the Medical University of South Carolina in Charleston, SC. In 2001 she was appointed as Research Assistant Professor in the Department of Pathology and Laboratory Medicine. In July 2003 she joined the Laboratory of Experimental Oncology at the IOSI in Bellinzona as senior investigator and she is at present Group Leader for the prostate cancer biology program.

Research Intrest

molecular mechanisms,cancer development, progression, prostate cancer development, Cell growth, differentiation processes, gene transcription, cellular proliferation, apoptosis, invasiveness, cancer progression, prostate cancer, clinical samples, diagnosis, prognosis, therapy oncogenic ETS factors

List of Publications

Carbone GM, McGuffie E, Napoli S, Flanagan CE, Dembech C, Negri U, Arcamone F, Capobianco ML, Catapano CV. DNA binding and antigene activity of a daunomycinâ€conjugated triplexâ€forming oligonucleotide targeting the P2 promoter of the human câ€myc gene. Nucleic acids research. 2004 Apr 15;32(8):2396-410.

Carbone GM, McGuffie EM, Collier A, Catapano CV. Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplexâ€forming oligonucleotide. Nucleic acids research. 2003 Feb 1;31(3):833-43.

Carbone GM, Napoli S, Valentini A, Cavalli F, Watson DK, Catapano CV. Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells. Nucleic acids research. 2004 Jan 1;32(14):4358-67.

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Giuseppina Carbone

Carbone GM, McGuffie EM, Collier A, Catapano CV. Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplexâ€forming oligonucleotide. Nucleic acids research. 2003 Feb 1;31(3):833-43.

Carbone GM, Napoli S, Valentini A, Cavalli F, Watson DK, Catapano CV. Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells. Nucleic acids research. 2004 Jan 1;32(14):4358-67.

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Giuseppina Carbone

Carbone GM, McGuffie EM, Collier A, Catapano CV. Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplexâ€forming oligonucleotide. Nucleic acids research. 2003 Feb 1;31(3):833-43.

Carbone GM, Napoli S, Valentini A, Cavalli F, Watson DK, Catapano CV. Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells. Nucleic acids research. 2004 Jan 1;32(14):4358-67.

Experts in Switzerland

Carbone GM, McGuffie EM, Collier A, Catapano CV. Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplexâ€forming oligonucleotide. Nucleic acids research. 2003 Feb 1;31(3):833-43.