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Dr. Shengmin Sang

Scientist
Center of Excellence in Post-Harvest Technologies
North Carolina Agricultural & Technical State University
United States of America

Scientist Diabetes and Endocrinology
Biography

EDUCATION: 1994 B.S., Shandong Normal University 1999 Ph.D., Shanghai Institute of Materia Medica, Chinese Academy of Sciences AREAS OF EXPERTISE: Metabolomics and dietary exposure biomarkers in cancer prevention research. Bioavailability and biotransformation studies of bioactive natural products in animals and humans. Development of new chemopreventive agents from dietary sources using in vitro and animal models. Mechanistic studies of bioactive food components on oxidative stress (keap1/Nrf2/ARE pathway) and carbonyl stress (Advanced Glycation End Products (AGEs) for the prevention of diabetic complications). Purification and structure determination of bioactive components from herbal medicine and functional foods. Standardization and quality control of herbal medicine and functional foods.  

Research Intrest

Colon Cancer Prevention, Obesity and Diabetes 

List of Publications
Chen, H.; Fu, J.; Chen, H.; Hu, Y.; Soroka, D.N.; Prigge, J.R; Schmidt, E.E.; Major, M.B.; Chen, X.; and Sang, S. Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo. Chem. Res. Toxicol. 2014, 27(9), 1575-1585.
Li, X.; Zheng, T.; Sang, S.; Lv, L. Quercetin Inhibits Advanced Glycation End Product Formation by Trapping Methylglyoxal and Glyoxal. J. Agric. Food Chem. 2014, 62(50), 12152-12158.
Wang, P.; Chen, H.; Zhu, Y.; McBride, J.; Fu, J.; Sang, S. Oat avenanthramide-C (2c) is metabolized by mice and the human microbiota into bioactive metabolites. J Nutr. 2015, 145 (2), 239-245.
Zhu, Y.; Zhao, Y.; Wang, P.; Ahmedna, M.; Sang, S. Bioactive ginger constituents alleviate protein glycation by trapping methylglyoxal. Chem. Res. Toxicol. 2015, 28 (9), 1842-1849.
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