Her group are interested in the structural and physical principles that govern assembly and stabilisation of complex viruses. As a model system we use adenovirus, a challenging specimen of interest both in basic virology and in nanobiomedicine. They approach the problem from an interdisciplinary point of view, combining biophysics, computational, structural and molecular biology techniques. Accurate knowledge of adenovirus structure and biology is fundamental to both the discovery of anti-adenovirus drugs and the design of new, efficient adenoviral therapeutic tools.
Macromolecular Structures