Barbara K. Felber

Vaccine Branch
The Center for Cancer Research
United States of America

Biography

Dr. Felber received her Ph.D. in molecular biology from the University of Bern, Switzerland. After carrying out postdoctoral studies in the Laboratory of Biochemistry, NCI Bethesda, she joined the Molecular Mechanisms of Carcinogenesis Laboratory, the NCI contract Basic Research Program, in 1985. In 1990, Dr. Felber established the Human Retrovirus Pathogenesis Group. In 1998, Dr. Felber received her tenure appointment and, in 1999, she joined the Center for Cancer Research, NCI. Her work focuses on the posttranscriptional mechanisms of gene regulation, use of cytokines in cancer and AIDS,and the development of DNA-based HIV vaccines.

Research Intrest

Clinical Research, Immunology, Molecular Biology and Biochemistry, Virology

List of Publications

Jalah R, Kulkarni V, Patel V, Rosati M, Alicea C, et al. (2014) DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques. PLoS ONE 9: e91550,

Kulkarni V, Valentin A, Rosati M, Alicea C, Singh AK, et al. (2014) Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques. PLoS ONE. 9: e86254,

Jalah R, Rosati M, Ganneru B, Pilkington GR, Valentin A, et al.(2013) The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production. J. Biol. Chem. 288: 6763-76.

Gegerfelt AS, Rosati M, Alicea C, Valentin A, Roth P, et al. (2007) Long-lasting decrease in viremia in macaques chronically infected with simian immunodeficiency virus SIVmac251 after therapeutic DNA immunization. J. Virol. 81: 1972-1979.

GrÃ¼ter P, Tabernero C, von Kobbe C, Schmitt C, Saavedra C, et al. (1998) TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol. Cell. 1: 649-59.

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