Anant Bahadur Patel

Scientist
Cellular and Molecular Biology
Centre for Cellular and Molecular Biology
India

Scientist Molecular Biology
Biography

Dr. Anant B. Patel obtained his master in Chemistry with Physical Chemistry specialization from Department of Chemistry, Banaras Hindu University in 1993 and Ph. D. in Chemistry entitled "NMR Studies of Biomolecular Systems" from the Department of Chemical Sciences, Tata Institute of Fundmamental Research / Mumbai University, Mumbai in 1999. He was a Postdoctoral Research Associate at the Magnetic Resonance Research Centre (MRRC), Yale University, New Haven, Connecticut, USA from 1999-2003. He served as Associate Research Scientist at Yale MRRC from 2003-2006.He joined the Centre for Cellular and Molecular Biology, Hyderabad as a senior scientist in June 2006. He has started in vivo NMR imaging and spectroscopy program in the institute and carrying out research in the field of in vivo NMR spectroscopy. His research interests are in trying to understand metabolic basis of various diseases/disorders related with nervous system. One major area of focus in his laboratory is in understanding how excitatory and inhibitory neurotransmission are affected during normal ageing and in different neurological conditions. The other areas of research in his laboratory include understanding the brain energy metabolism in diabetes and developing MRI contrast agents.

Research Intrest

Anant Bahadur Patel's research interests are in trying to understand metabolic basis of various diseases/disorders related with nervous system. One major area of focus in his laboratory is in understanding how excitatory and inhibitory neurotransmission are affected during normal ageing and in different neurological conditions. The other areas of research in his laboratory include understanding the brain energy metabolism in diabetes and developing MRI contrast agents.

List of Publications
Bagga P, Behar KL, Mason GF, De Feyter HM, Rothman DL, Patel AB (2014) Characterization of Cerebral Glutamine Uptake from Blood in the Mouse Brain: Implications for Metabolic Modeling of 13C NMR Data. J Cereb Blood Flow Metab 34: 1666-1672.
Veeraiah P, Noronha JM, Maitra S, Bagga P, Khandelwal N, Chakravarty S, Kumar A, Patel AB (2014) Dysfunctional Glutamatergic and GABAergic Activities in Prefrontal Cortex of Mice in Social Defeat Model of Depression. Biol Psychiatry 76: 231-238.
Patel AB, Lai JCK, Chowdhury GMI, Hyder F, Rothman DL, et al. (2014) Direct evidence for activity-dependent glucose phosphorylation in neurons with implications for the astrocyte-to-neuron lactate shuttle. Proc Natl Acad Sci USA 111: 5385-5390.